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Diclazepam

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Description

Diclazepam (Ro5-3448), also known as chlorodiazepam and 2′-chloro-diazepam

THE PRODUCTS OFFERED BY NORTHERN SCIENCE ARE INTENDED FOR:

LABORATORY RESEARCH USE ONLY.

THESE CHEMICALS ARE TOXIC AND ARE NOT FOR HUMAN CONSUMPTION, HUMAN TRIALS, AND ANIMAL STUDIES.

Clinical data
Routes of
administration
NONE
Legal status
Legal status
Pharmacokinetic data
Bioavailability ?
Metabolism Hepatic
Elimination half-life ~42 hours[1]
Excretion Renal
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
Formula C16H12Cl2N2O
Molar mass 319.185 g/mol g·mol−1
3D model (JSmol)

References

 

  • Moosmann B, Bisel P, Auwärter V (July–August 2014). “Characterization of the designer benzodiazepine diclazepam and preliminary data on its metabolism and pharmacokinetics”. Drug Testing and Analysis. 6 (7–8): 757–63. doi:10.1002/dta.1628. PMID 24604775.
  • US 3136815, “Amino substituted benzophenone oximes and derivatives thereof”
  • Madeleine Pettersson Bergstrand; Anders Helander; Therese Hansson; Olof Beck (2016). “Detectability of designer benzodiazepines in CEDIA, EMIT II Plus, HEIA, and KIMS II immunochemical screening assays”. Drug Testing and Analysis. 9 (4): 640–645. doi:10.1002/dta.2003. PMID 27366870.
  • Høiseth, Gudrun; Tuv, Silja Skogstad; Karinen, Ritva (2016). “Blood concentrations of new designer benzodiazepines in forensic cases”. Forensic Science International. 268: 35–38. doi:10.1016/j.forsciint.2016.09.006. PMID 27685473.
  • Manchester, Kieran R.; Maskell, Peter D.; Waters, Laura (2018). “Experimental versus theoretical log D7.4, pKa and plasma protein binding values for benzodiazepines appearing as new psychoactive substances”. Drug Testing and Analysis. 10 (8): 1258–1269. doi:10.1002/dta.2387. ISSN 1942-7611. PMID 29582576.
  • Bareggi SR, Truci G, Leva S, Zecca L, Pirola R, Smirne S (1988). “Pharmacokinetics and bioavailability of intravenous and oral chlordesmethyldiazepam in humans”. European Journal of Clinical Pharmacology. 34 (1): 109–112. doi:10.1007/bf01061430. PMID 2896126.

THE PRODUCTS OFFERED BY NORTHERN SCIENCE ARE INTENDED FOR:

LABORATORY RESEARCH USE ONLY.

THESE CHEMICALS ARE TOXIC AND ARE NOT FOR HUMAN CONSUMPTION, HUMAN TRIALS, AND ANIMAL STUDIES.

Additional information

Weight

1 Gram, 10 Grams, 100 Grams, 20 Grams, 5 Grams, 50 Grams, 500 Grams, 500 mg